Multiple Vulnerabilities to Health Disparities and Incident Heart Failure Hospitalization in the REGARDS Study.

Title
Publication TypeJournal Article
Year of Publication2020
AuthorsPinheiro LC, Reshetnyak E, Sterling MR, Levitan EB, Safford MM, Goyal P
JournalCirc Cardiovasc Qual Outcomes
PaginationCIRCOUTCOMES119006438
Date Published2020 Jul 24
ISSN1941-7705
Abstract

Background Socially determined vulnerabilities (SDVs) to health disparities often cluster within the same individual. SDVs are separately associated with increased risk of heart failure (HF). The objective of this study was to determine the cumulative effect of SDVs to health disparities on incident HF hospitalization. Methods and Results Using the REGARDS (Reasons for Geographic and Racial Differences in Stroke) cohort study, we studied 25 790 participants without known HF and followed them for 10+ years. Our primary outcome was an incident HF hospitalization through December 31, 2016. Guided by the Healthy People 2020 framework for social determinants of health, we examined 10 potential SDVs. We retained SDVs associated with incident HF hospitalization (

DOI10.1161/CIRCOUTCOMES.119.006438
Alternate JournalCirc Cardiovasc Qual Outcomes
PubMed ID32703013
Grant ListR01 HL080477 / HL / NHLBI NIH HHS / United States